교수소개

교수

강하라
직책/직급
교수
주전공
분자생물학
담당과목
분자생물학, 종양생물학, 고급분자생물학
전화번호
032-835-8238
이메일
harakang@inu.ac.kr
홈페이지
-
학력

2009.05.08 University of Utah  (이학박사)

2002.02.15 광주과학기술원  (이학석사)

2000.02.15 성균관대학교  (이학사)

경력

2011.07 ~ 2012.02 University of California at San Francisco (박사후연구원)

2009.06 ~ 2011.06 Tufts Medical Center (박사후연구원)

연구실적
<논문> 

Platelet-derived growth factor-stimulated pulmonary artery smooth muscle cells regulate pulmonary artery endothelial cell dysfunction through extracellular vesicle miR-409-5p, BIOLOGICAL CHEMISTRY , 제405권(집) , 제3호 , PP.203~215 , 2024.03.25

Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges, JOURNAL OF BIOMEDICAL SCIENCE , 제30권(집) , 제1호 , 2023.10.16

Nucleolin Regulates Pulmonary Artery Smooth Muscle Cell Proliferation under Hypoxia by Modulating miRNA Expression, Cells , 제12권(집) , 제5호 , 2023.03.01

Exosome-based treatment for atherosclerosis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제23권(집) , 제2호 , PP.1002~ , 2022.01.17

Role of MicroRNAs and Long Non-Coding RNAs in Sarcopenia, Cells , 제11권(집) , 제2호 , PP.187~ , 2022.01.06

Deficiency of Tristetraprolin Triggers Hyperthermia through Enhancing Hypothalamic Inflammation, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제22권(집) , 제7호 , 2021.04.01

BMP-Induced MicroRNA-101 Expression Regulates Vascular Smooth Muscle Cell Migration, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제21권(집) , 제13호 , PP.4764~ , 2020.07.04

Hypoxia-induced miR-1260b Regulates Vascular Smooth Muscle Cell Proliferation by Targeting GDF11, BMB Reports , 제53권(집) , 제4호 , PP.206~211 , 2020.04.30

Vascular Smooth Muscle Cell-Derived Exosomal MicroRNAs Regulate Endothelial Cell Migration Under PDGF Stimulation, Cells , 제9권(집) , 제3호 , PP.639~ , 2020.03.06

miR-92b-3p-TSC1 axis is critical for mTOR signaling-mediated vascular smooth muscle cell proliferation induced by hypoxia, CELL DEATH AND DIFFERENTIATION , 제26권(집) , 제9호 , PP.1782~1795 , 2019.09.01

Hypoxia Promotes Vascular Smooth Muscle Cell Proliferation through microRNA-Mediated Suppression of Cyclin-Dependent Kinase Inhibitors, Cells , 제8권(집) , 제8호 , PP.802~ , 2019.08.01

MicroRNA-Mediated Health-Promoting Effects of Phytochemicals, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제20권(집) , 제10호 , PP.2535~ , 2019.05.02

Hypoxia-induced regulation of mTOR signaling by miR-7 targeting REDD1., JOURNAL OF CELLULAR BIOCHEMISTRY , 제120권(집) , 제3호 , PP.4523~4532 , 2019.03.01

Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase, Nature Communications , 제9권(집) , 2018.11.19

Stat5 phosphorylation is responsible for the excessivepotency of HB-EGF, JOURNAL OF CELLULAR BIOCHEMISTRY , 제119권(집) , 제7호 , PP.5297~5307 , 2018.03.30

Role of MicroRNAs in TGF-beta Signaling Pathway-Mediated Pulmonary Fibrosis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 제18권(집) , 제12호 , 2017.11.25

Suppression of lytic replication of Kaposi's sarcoma-associated herpesvirus by autophagy during initial infection in NIH 3T3 fibroblasts., ARCHIVES OF VIROLOGY , 제161권(집) , 제3호 , PP.595~604 , 2016.03.01

Crystal structure and modeling of the tetrahedral intermediate state of methylmalonate-semialdehyde dehydrogenase (MMSDH) from Oceanimonas doudoroffii, JOURNAL OF MICROBIOLOGY , 제54권(집) , 제2호 , PP.114~121 , 2016.02.02

miR-195a Inhibits Adipocyte Differentiation by Targeting the Preadipogenic Determinator Zfp423, JOURNAL OF CELLULAR BIOCHEMISTRY , 제116권(집) , 제11호 , PP.2589~2597 , 2015.11.01

miR-142-3p Is a Regulator of the TGFβ-Mediated Vascular Smooth Muscle Cell Phenotype, JOURNAL OF CELLULAR BIOCHEMISTRY , 제116권(집) , 제10호 , PP.2325~2333 , 2015.10.01

Cucurbitacin I Attenuates Cardiomyocyte Hypertrophy via Inhibition of Connective Tissue Growth Factor (CCN2) and TGF- β/Smads Signalings, PLoS One , 제10권(집) , 제8호 , PP.01362~36 , 2015.08.21

Kaempferol inhibits vascular smooth muscle cell migrationby modulating BMP-mediated miR-21 expression, MOLECULAR AND CELLULAR BIOCHEMISTRY , 제407권(집) , PP.143~149 , 2015.08.17

The role of microRNAs in cell fate determination of mesenchymal stem cells: balancing adipogenesis and osteogenesis, BMB Reports , 제48권(집) , 제6호 , PP.319~323 , 2015.06.30

Functions of the bone morphogenetic protein signaling pathway through microRNAs, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE , 제35권(집) , 제3호 , PP.563~568 , 2015.03.01

Enhancement of Potency and Stability of Human Extracellular Superoxide Dismutase, BMB Reports , 제48권(집) , 제2호 , PP.91~96 , 2015.02.20

Down-Regulation of miR-96 by Bone Morphogenetic Protein Signaling is Critical for Vascular Smooth Muscle Cell Phenotype Modulation, JOURNAL OF CELLULAR BIOCHEMISTRY , 제115권(집) , 제5호 , PP.889~895 , 2014.05.01

TGFβSignaling-mediated MicroRNA Regulation in VascularSmooth Muscle Cells, Journal of Lifestyle Medicine , 제3권(집) , 제2호 , PP.80~84 , 2013.12.31

miR-15b induced by platelet-derived growth factor signaling is required for vascular smooth muscle cell proliferation, BMB REPORTS , 제46권(집) , 제11호 , PP.550~554 , 2013.11.28

Differential inhibitory effects of two Raf-targeting drugs, sorafenib and PLX4720, on the growth of multidrug-resistant cells, MOLECULAR AND CELLULAR BIOCHEMISTRY , 제372권(집) , 제1호 , PP.65~74 , 2013.01.01

Effects of Heavy Metals on Plant Growths and Pigment Contents in Arabidopsis thaliana, PLANT PATHOLOGY JOURNAL , 제28권(집) , 제4호 , PP.446~452 , 2012.12.01

Inhibition of MicroRNA-302 (miR-302) by Bone Morphogenetic Protein 4 (BMP4) Facilitates the BMP Signaling Pathway., Journal of Biological Chemistry , 제287권(집) , 제46호 , PP.38656~38664 , 2012.11.09

MicroRNA regulation of smooth muscle gene expression and phenotype., CURRENT OPINION IN HEMATOLOGY , 제19권(집) , 제3호 , PP.224~231 , 2012.05.01

Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins, JOURNAL OF BIOLOGICAL CHEMISTRY , 제287권(집) , 제6호 , PP.3976~86 , 2012.02.02

The Amiloride Derivative Phenamil Attenuates Pulmonary Vascular Remodeling by Activating NFAT and the Bone Morphogenetic Protein Signaling Pathway, MOLECULAR AND CELLULAR BIOLOGY , 제31권(집) , 제3호 , PP.517~530 , 2011.02.01

<저서> 

Quantitative Real-Time PCR Analysis of MicroRNAs and Their Precursors Regulated by TGF-β Signaling, Springer New York , 2016.04.01

The Enzymes, Vol. 32, Elsevier , 2012.12.01